Regulated Cannabis Testing
Keystone Labs offers the following Microbial and Analytical Services to licensed producers, personal growers and medical users Medicinal Cannabis under the Access to Cannabis for Medical Purpose Regulations (ACMPR).
Document the specific physical characteristics of the sample. For example: dried and milled Cannabis sativa spp. Dark green to light green and tan colored Flowering plant particulates with characteristic aroma having citrus and pine overtones.
Foreign Matter Inspection
Visual inspection of raw cannabis material will confirm absence of foreign material contamination or evidence of spoilage. Absence of stalks, insects and other vermin. Visual inspection should confirm the absence of pests and extraneous substances.
This is the weight of the water relative to the total weight of the sample. Determination of moisture content is assessed via loss-on-drying. Laboratory samples are reported in both dry and wet weight. Moisture analysis needs 24 hours to complete and is required for Cannabinoid potency determination and profiling.
Cannabinoid Profile and Potency Testing
Health Canada requires that licensed producers test each batch or lot of cannabis for potency, and report the total Tetrahydrocannabinol (THC) and Cannabidiol (CBD) on the packaging and to their patients. Keystone Labs offers accurate quantification of 10 cannabinoids (soon to be 15) using ULTRA high pressure liquid chromatography (UHPLC). THE UHPLC does not heat up the sample therefore any acid cannabinoid compounds, such as THC-A will remain in their natural form. This allows quantification of all the acid (THC-A) and neutral (THC) forms of the client’s cannabinoid profile and potency;
- D9 – Tetrahydrocannabinol (D9-THC)
- Tetrahydrocannabinolic acid (THCA)
- Cannabidiol (CBD)
- Cannabidiolic acid (CBDA)
- Cannabigerol (CBG)
- Cannabigerolic acid (CBGA)
- Cannabinol (CBN)
- Cannabichromere (CBC)
- Tetrahydrocannabivarin (THCV)
- Cannabidivarin (CBDV)
- Cannabichromenic acid (CBCA)
- Tetrahydrocannabivarin acid (THCVA)
- Cannabidivarin acid (CBDVA)
- Cannabigerovarin acid (CBGVA)
- D8 – Tetrahydrocannabinol (D8-THC)
Our microbiological screening program ensures the safety of cannabis by testing for the level of various microorganisms which may be present in each sample. Health Canada has established tolerance limits for microbiological contamination in cannabis. Keystone Labs has extensive years of experience testing for microbial contamination and identification. Testing is performed according to current USP protocols.
- Total aerobic microbial counts (TAMC) 500,000 CFU/g
- Total yeast and mold counts (TYMC) 50,000 CFU/g
- Bile-Tolerant Gram-negative bacteria 10,000 CFU/g
Absence of Microbial Contaminants
- Escherichia coli Absent from 1 gram
- Staphylococcus aureus Absent from 1 gram
- Pseudomonas aeruginosa Absent from 1 gram
Aflatoxins are a family of naturally occurring toxins produced by Aspergillus flavus and Aspergillus parasiticus, which are abundant in warm and humid environments. These mycotoxins are poisonous and cancer-causing chemicals. Keystone Labs follows the current USP <561> protocol to detect aflatoxins.
We are able to detect and identify trace amounts of metals and heavy metals which should not be present in the finished product.
While many growers and collective dispensaries take care to provide safe, effective products, there are numerous reports of the presence of pesticides in purchased cannabis. These tested are used to show the absence of pesticides.
Proposed Target List for Pesticide Testing in Cannabis
- DDVP (Dichlorvos)
- Methyl parathion
- Piperonyl butoxide
Terpenes (Coming Soon)
Terpenes are fragrant oils that give cannabis it aromatic and flavor characteristics. These oils are secreted by the tricomes. Like cannabinoids, terpenes bind to receptors in the brain and give rise to various effects. Science and technology will give us a better understanding of the beneficial interactions between terpenes and cannabinoids.
A list of the terpenes detected and quantitated with a Gas Chromatograph/Mass Spectrometry (GC-MS):
- (-) Alpha-Bisabolol
- (- /+) Borneal
- (-) Caryophyllene Oxide
- (1R)-Endo-(+)-Fenchyl Alcohol
- Ocimene (mixture of Isomers)
- Sabinene Hydrate
- Terpineol (mixture of isomers)
Residual Solvents Analysis for Medical Cannabis Concentrates (Coming Soon)
Previously referred to as organic volatile impurities (OVIs), residual solvents are trace level chemical residues that are used or produced in the manufacturing of concentrated cannabis extracts from the plant. Many different solvents are used for the production of Medical Cannabis concentrates.
A list of some of the solvents that can be detected by using a Gas Chromatograph in combination with head-sample sampling: